Eating Ultra-Processed Foods: A Growing Threat of Early Death

Estimated read time 5 min read

Ultra-processed foods (UPFs) have become a cornerstone of modern diets, valued for their convenience and long shelf life. However, a growing body of research suggests that these foods may pose significant risks to health, including an increased likelihood of premature death and a range of chronic conditions.

This analysis explores the definition of UPFs, the evidence linking them to early mortality, other associated health risks, potential mechanisms behind these effects, and strategies to reduce their consumption.

Defining Ultra-Processed Foods

Ultra-processed foods are products that undergo multiple industrial processes and contain ingredients not typically found in home kitchens, such as artificial flavors, emulsifiers, and preservatives. The NOVA classification system, developed in Brazil in 2009, categorizes foods into four groups, with UPFs in the fourth category. Examples include:

Category

Examples

Packaged Snacks

Chips, cookies, candy

Beverages

Sodas, energy drinks, artificially sweetened drinks

Ready Meals

Frozen dinners, fast food

Processed Meats

Hot dogs, sausages, bacon

Breakfast Foods

Sugary cereals, pastries

Desserts

Ice cream, packaged cakes

UPFs are typically high in added sugars, sodium, and unhealthy fats while being low in fiber, vitamins, and minerals. In the UK and US, UPFs account for over 50% of daily energy intake, with some groups consuming up to 80% (Ultra-processed food linked to 32 harmful effects).

Evidence Linking UPFs to Early Death

Research consistently shows an association between high UPF consumption and premature mortality. A 2025 meta-analysis published in the American Journal of Preventive Medicine analyzed data from over 240,000 individuals across eight countries.

It found that for every 10% increase in UPFs in a person’s diet, the risk of dying before age 75 increases by approximately 2.7–3% (Ultra-processed food increases risk). Key findings include:

Country

Premature Deaths Attributable to UPFs

Annual Deaths

UK

13.8% 17,781

US

13.7% 124,107

Canada

10.9%

Brazil

5% 57,000 (2019)

Colombia

4%

Chile

6%

A 2023 study in Brazil estimated that UPFs were responsible for 10.5% of premature deaths among adults aged 30–69, equating to approximately 57,000 deaths annually (Ultra-processed foods and early death). Reducing UPF intake by 10–50% could prevent 5,900 to 29,300 deaths, respectively.

A 30-year US study published in The BMJ in 2024 found that higher consumption of UPFs, particularly processed meats, sugary drinks, dairy-based desserts, and sugary breakfast foods, is linked to a slightly higher risk of all-cause mortality (30-year US study). The study noted a 4% higher risk of death overall and a 9% greater risk of death from non-cancer, non-heart disease causes.

A 2019 Spanish study of 19,899 university graduates found that those consuming more than four servings of UPFs daily were 62% more likely to die over 10.4 years compared to those consuming less than two servings (Ultra-processed foods: how bad).

These studies are observational, meaning they show associations rather than causation. Some experts caution that other factors, such as lifestyle or socioeconomic status, may contribute to these outcomes (Ultra-processed foods may be linked).

Other Health Risks Associated with UPFs

UPFs are linked to a broad spectrum of health issues beyond early death. A 2024 umbrella review in The BMJ, analyzing 45 meta-analyses with nearly 10 million participants, identified 32 adverse health outcomes (Ultra-processed food exposure). Key risks include:

Health Outcome

Risk Increase

Evidence Strength

Cardiovascular Disease Death

50%

Convincing (Class I)

Heart Disease Death

40–66%

Highly Suggestive (Class II)

Type 2 Diabetes

12–53%

Convincing (Class I)

Anxiety & Mental Disorders

48–53%

Convincing (Class I)

Depression

22%

Suggestive (Class III)

Obesity

40–66%

Highly Suggestive (Class II)

Cognitive Impairment

Increased

Suggestive (Class III)

Breast & Colorectal Cancer

Increased

Suggestive (Class III)

  • Cardiovascular Diseases: UPFs are associated with a 50% increased risk of cardiovascular disease-related death and a 40–66% higher risk of heart disease-related death (New review links).

  • Cancer: Studies link UPFs to higher risks of breast and colorectal cancers (What we know).

  • Type 2 Diabetes: A 12–53% increased risk is reported, driven by high sugar content and low fiber (Ultraprocessed Foods: Are They Bad).

  • Mental Health: UPFs are linked to a 48–53% higher risk of anxiety and common mental disorders, and a 22% increased risk of depression (What doctors wish).

  • Obesity: UPFs’ high calorie content and low satiety contribute to weight gain (Health Risks of Eating).

  • Cognitive Decline: A study from the REGARDS project found links to cognitive impairment and strokes (Ultra-processed foods? Just say no).

  • Other Issues: UPFs are associated with sleep problems, inflammatory bowel disease, and gut health issues (How Do Ultraprocessed).

Mechanisms Behind the Health Risks

The precise reasons why UPFs are harmful are not fully understood, but several factors are likely involved:

  1. Poor Nutritional Quality: UPFs are high in added sugars, sodium, and saturated fats, and low in fiber, vitamins, and minerals, contributing to chronic diseases (What doctors wish).

  2. Additives: Ingredients like emulsifiers, artificial sweeteners, and preservatives may disrupt gut health or metabolism (Ultra-processed food increases risk).

  3. Processing Effects: Industrial processing alters food structure, making UPFs more palatable and easier to overeat, leading to weight gain (How Do Ultraprocessed).

  4. Dietary Displacement: High UPF consumption reduces intake of nutrient-rich whole foods, exacerbating health risks (Ultra-processed foods: how bad).

Recommendations for Reducing UPF Consumption

To mitigate the risks associated with UPFs, experts suggest the following:

  1. Read Food Labels: Choose products with minimal ingredients and avoid those with extensive additive lists.

  2. Cook at Home: Preparing meals from scratch allows control over ingredients and reduces reliance on UPFs.

  3. Prioritize Whole Foods: Focus on fruits, vegetables, whole grains, lean proteins, and healthy fats, such as those in a Mediterranean-style diet.

  4. Limit Snacking: Many UPFs are marketed as snacks, so reducing snacking can lower intake.

  5. Advocate for Policy Changes: Support regulations on UPF marketing, especially to children, and taxes to discourage consumption (Ultra-processed food increases risk).

Conclusion

The evidence linking ultra-processed foods to early death and other health risks is substantial, with studies showing associations with premature mortality, cardiovascular diseases, cancer, type 2 diabetes, mental health disorders, obesity, and cognitive decline.

While these studies are observational and cannot prove causation, the consistency of findings across large populations underscores the need for caution. Reducing UPF consumption through informed dietary choices and supportive public health policies can help mitigate these risks, promoting better health and longevity.

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